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    World Map

    Where these substances come from. Brighter countries have more origins. Click to explore.

    Simple World Map Author: Al MacDonald Editor: Fritz Lekschas License: CC BY-SA 3.0 ID: ISO 3166-1 or "_[a-zA-Z]" if an ISO code is not available
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    substances

    By origin

    Unknown

    Ajo Sacha, Chiric Sanango, Guayusa, Sinicuichi, Voacanga africana

    Amazon Basin

    Ayahuasca, Rapé

    Andean highlands

    Coca, San Pedro

    Mesoamerica

    Morning Glory, Psilocybin Mushrooms

    Berkeley, California (Shulgin lab)

    2C-B

    The Sonoran Desert Toad

    5-MeO-DMT

    Northern Hemisphere (boreal forests)

    Amanita Muscaria

    Southern and Central Europe

    Belladonna

    Nile River Valley

    Blue Lotus

    Geographic Distribution and Ethnographic Documentation

    Bobinsana

    Central Asia

    Cannabis

    as free CBD (the active form) and as cannabidiolic acid (CBDA), the carboxylic acid precursor that is converted to active CBD through heating via decarboxylation[3][5]. The proportion of CBD relative to THC varies dramatically across different cannabis genetics, with this variation rooted in polymorphic differences in cannabinoid synthase genes distributed across multiple chromosomes of the cannabis genome, creating a genotypically complex landscape where THC and CBD content represent independently inherited traits[29]. Industrial hemp varieties selected for agricultural production have been specifically bred to produce high CBD and low THC content, typically achieving ratios of 20:1 or higher (CBD:THC), whereas recreational cannabis strains commonly exhibit the reverse ratio with higher THC relative to CBD[3]. Geographic distribution of cannabis growing regions extends globally across temperate and subtropical latitudes, though quality and regulatory status of cultivation varies dramatically by jurisdiction. Hemp cultivation for CBD extraction has rapidly expanded across North America and Europe following legalization of hemp-derived products, with industrialized production now occurring in numerous countries including Canada, the European Union member states, and increasingly throughout Asia.

    CBD

    Global (tropical and temperate)

    Datura

    Amazon Basin (as plant compounds)

    DMT

    The Chontal Indigenous Practice of Oneiromancy

    Dream Herb

    Indian subcontinent

    Hawaiian Baby Woodrose

    Mediterranean and Western Asia

    Henbane

    Central Africa

    Iboga

    South Africa (Western Cape)

    Kanna

    Western Pacific Islands

    Kava

    Detroit, Michigan (Parke-Davis)

    Ketamine

    Southeast Asia

    Kratom

    Basel, Switzerland (Sandoz Labs)

    LSD

    Chemistry, Medicine, and Law

    Mambe and Ambil

    Mediterranean Basin

    Mandragora

    Darmstadt, Germany (Merck)

    MDMA

    Eastern Mediterranean

    Opium Poppy

    Chihuahuan Desert

    Peyote

    Sierra Mazateca, Oaxaca

    Salvia Divinorum

    Central Asia and Middle East

    Syrian Rue

    First cannabinoid isolation (Adams)

    THC

    possession of up to 1 gram results in fines up to 280 euros, while possession and distribution of larger quantities can be punished with up to 15 years imprisonment[1][1]. Poland banned Leonotis leonurus in March 2009, with possession and distribution resulting in criminal charges[1]. These European prohibitions represent the only known modern drug scheduling of wild dagga globally, reflecting perhaps heightened concern about commercial herbal markets and synthetic cannabinoid adulteration in these specific jurisdictions.

    Wild Dagga

    Orinoco Basin, South America

    Yopo