Reference
Key terms and concepts used throughout Psylopedia, defined plainly and without jargon.
A structured container for intentional psychedelic use, often guided by a facilitator, shaman, or therapist.
A drug or chemical whose manufacture, possession, or use is regulated by law.
A network of interconnected brain regions most active during rest, mind-wandering, and self-referential thinking.
A class of substances that produce feelings of detachment from the body and environment.
A naturally occurring tryptamine found in hundreds of plant and animal species, producing intense but brief psychedelic experiences when smoked.
A temporary experience during which one's sense of individual self dissolves.
A substance used to occasion spiritual or mystical experiences, from Greek "generating the divine within."
A broad term for substances that alter perception, mood, and cognition.
A set of practical strategies and principles aimed at reducing the negative consequences of substance use.
The primary psychoactive alkaloid found in the root bark of the Tabernanthe iboga shrub, studied for its potential to interrupt opioid addiction.
The process of making sense of and incorporating insights from a psychedelic experience into daily life.
A substance that blocks the enzyme monoamine oxidase, which normally breaks down neurotransmitters like serotonin, dopamine, and norepinephrine.
A naturally occurring psychedelic alkaloid found in several cacti, most notably peyote and San Pedro.
The practice of consuming sub-perceptual amounts of a psychedelic substance, typically 1/10th to 1/20th of a full dose, on a regular schedule.
The brain's ability to form and reorganize synaptic connections, especially in response to learning, experience, or injury.
The pharmacologically active metabolite of psilocybin, responsible for the psychedelic effects of magic mushrooms.
Any substance that crosses the blood-brain barrier and affects brain function, altering perception, mood, consciousness, cognition, or behavior.
Physical release (often vomiting, sometimes crying, sweating, or shaking) that commonly occurs during ayahuasca ceremonies.
The primary psychoactive compound in Salvia divinorum, unique among natural psychedelics for acting on kappa-opioid receptors.
Relating to or affecting the neurotransmitter serotonin (5-hydroxytryptamine).
The combination of one's internal state ("set," short for mindset) and external environment ("setting") during a psychedelic experience.
A class of organic compounds that share an indole ring structure, including many well-known psychedelics.
